2. Signaling Pathways
  3. Stem Cell/Wnt
  4. Hippo (MST)
  5. Hippo (MST) Inhibitor

Hippo (MST) Inhibitor

Hippo (MST) Inhibitors (5):

Cat. No. Product Name Effect Purity
  • HY-100526
    XMU-MP-1
    		Inhibitor 99.51%
    XMU-MP-1 is a reversible and selective MST1/2 inhibitor with IC50s of 71.1 and 38.1 nM, respectively.
  • HY-128206
    I3MT-3
    		Inhibitor 99.98%
    I3MT-3 (HMPSNE) is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC50=2.7 μM). I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes. I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST.
  • HY-151257
    IHMT-MST1-58
    		Inhibitor 99.05%
    IHMT-MST1-58 is a potent, selective mammalian and orally active STE20-like protein 1 kinase (MST1) inhibitor with IC50 value of 23 nM. IHMT-MST1-58 can be used for the research of Type 1/2 diabetes.
  • HY-157932
    MR24
    		Inhibitor
    MR24, a G-5555 (HY-19635) derivative, is a mammalian STE20-like (MST) kinase inhibitor. MR24 selectively target MST3/4, with EC50 values of 57 and 583 nM, respectively.
  • HY-160211
    JA310
    		Inhibitor
    JA310 is a highly selective MST3 kinase inhibitor. JA310 has high cellular potency against MST3 with an EC50 value of 106 nM.